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Application of Component-resolved Diagnostics(CRD) in Food Allergy

Accurately diagnosing a patient with a possible food allergy is important to avoid unnecessary dietary restrictions and prevent life-threatening reactions. Routine testing modalities have limited accuracy, and an oral food challenge is often required to make a definitive diagnosis. Given that they are labour intensive and associated with risks of inducing an allergic reaction, several alternative diagnostic tests have been investigated. Component-resolved diagnostic (CRD) is a diagnostic test to detect specific IgE against individual allergen molecules or components using purified native or recombinant allergens. CRD has shown promise to improve diagnostics and has entered into clinical practice.